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L-Serine Powder

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In stock

Price From: FROM $13.96

Ships today if ordered in the next 8 hours and 42 minutes!

L-Serine Powder


  • Pure powder
  • Nonessential amino acid
  • Natural relaxant
  • Taste

  • Mixability

Serine is a nonessential amino acid that promotes overall physical and mental well being.


Serving Size & Timing

This supplement should be taken in servings of 2000mg, once per day.

Nutritional Information

Supplement Facts

Serving size: 2000 milligrams
Serving per container: *
Amount Per Serving % Daily Value**
L-Serine 2000mg *
* Daily Value not established.
** Based on 2,000 calorie diet


Sugar, soy, dairy, yeast, gluten, corn and additives.

As a dietary supplement, take 2000mg (rounded 1/2 tsp) daily, or as directed by physician.

US Standard Measuring Spoons
Spoon Size(level) milligrams
1/4 teaspoon 687
1/2 teaspoon 1375
1 teaspoon 2750



This supplement has no fillers of any kind present in it.


This supplement can cause nausea, insomnia and indigestion. While side effects are rare, taking too much of this supplement can result in serious issues such as cerebral allergies and suppression of the immune system. Women who are pregnant or nursing should not take this product.


This supplement will dissolve easily in water and has no discernible taste. It can be mixed with water or juice and then consumed. It should be stored in an area that is free from light, heat and moisture.

California residents: Click here for Proposition 65 warning.

Customer Reviews

Trouble Dissolving Powder
I have ALS and ordered L-Serine powder. The first time I took it, I happened to be drinking a milkshake, so I mixed in some L-Serine powder and it worked well. The next morning, I put some in orange juice and it all sort of congealed into a solid wafer at the bottom of the glass. I couldn't swallow that. Last night, I put some in a glass of milk - same result, solid wafer. I've since read some reviews here on your site and found others put the powder in plain water, coffee, even oatmeal. I found no info in Knowledge Base regarding L-Serine. I have sent a request for more info to Bulk Supplements support.

I ordered through Amazon (same price as here). Shipping was fast. I haven't taken enough of the supplement to comment on results.*

On 4/12/2019 John said...

El Serine
Love this product. This is the third month I have ordered El Serine from Bulk Supplements.
I love the quality of the product and I love how quickly the product arrives. It always surprises me. I am always happy with the pricing.*

On 12/7/2018 Jennifer said...

Fast delivery good product
Delivery came fairly quick and product was exactly as advertised. Greatly help with my tingling in my hands. Highly recommend *

On 11/8/2018 John R said...

Pesticide Protection Plan
Pesticides work by depleting l-serine in the body....among a few other amino acids.

I got my order a day earlier than promised, love the quality of the supps I ordered, and began feeling mentally stronger after the first day. It's one-stop shopping here! *

On 7/16/2018 Maureen said...

Positive review
First order came quickly. Really like the product.*

On 2/20/2018 Robin Weeks said...

Great Product
This is simply an awesome quality product. Having bought the same product for almost a year and 20Kg later, I don't think there is anything close to it in the market!*

On 2/8/2018 Carlos said...

Best brain food
This product dissolves well in hot water. It doesn’t have a taste in my opinion. Putting it in coffee doesn’t effect the taste if using 1/2 tsp.
Great to get you focused. An amino acid that’s in a simple powder form.*

On 12/12/2017 RP said...

L-serene is critical for me
This is product that I need to take to clam/relax my nervous/brain system as I have a bodily L-serene deficiency. Taking this bulk powder form is the purest way to absorb it and it is easy to mix in water and drink and cost effective. There is no taste. It is the product for me!*

On 12/11/2017 Donna said...

I am pleased
I was told of L-Serine for good memory function and about ordering the powder from this site. I was very pleased with how easy it was to order and the clear format. The product was affordable, arrived quickly and in good condition, and the packaging is simple, easy to read, and easy to store. Time will tell if the product works as described on the internet by many doctors, researchers, and scientists, but that will not be any reflection on Bulk Supplements, as they only delivered the product, and they did a great job at that!*

On 11/1/2017 Tracy said...

My wife has ALS/Lou Gehrig's Disease. Her neurologist recommended she take L-Serine as a supplement to possibly help slow progression in conjunction with Riluzole (the only FDA approved medication for this disease). She takes 30 gm (yes, that's 30 grams) per day. She has been taking L-Serine for about 8 months and it has helped her maintain her weight. Occasionally she has stomach issues.*

On 5/25/2017 William said...

Prompt Shipments

I have made two orders through Bulk Shipments since the beginning of 2017. They both shipped immediately and arrived in just three days from California to New England. Thank you Bulk Supplements for being so efficient with your in-house logistics!


On 3/11/2017 garret said...

I ordered this product after reading about it's properties to prevent dementia and age related neurological deficits.
This product arrive quickly and beautifully packaged. It is tasteless and mixes with my morning coffee.
In today's world of environmentally instigated illness, it is great to know a product of this availability is offered by a company with such high standards. Thanks for a great product.*

On 2/24/2017 Pamela said...

I started taking L-Serine for several months ago, in the hope of avoiding the Alzheimer's Disease that afflicted my uncle. I have just received my second shipment. I dissolve it in my morning coffee or add it to my oatmeal. It dissolves very easily. It seems to add a slight sweetness, which I do not find disagreable.*

On 2/22/2017 judith said...

Great Seervice
I just received my second shipment of serine powder. Doing great. Have got my good friend who's wife has early alzheimers to start using the products. He is so impressed with your service he has ordered many other products. Keep up the good work!*

On 12/24/2016 Robert Gherardi said...

L-Serine Powder
Our family has recently been devastated by the diagnosis of Benson's Syndrome in one of our beloved members. She is only 59 years old. While Benson's is not hereditary, we are told, it has shaken all of us into the realization that if there is SOMETHING we might do to help brain function then we should try it. L-Serine came to our attention. After much research we landed on this site and were impressed by the quality and the pureness of the products. My husband and I are taking it as well as our recently diagnosed loved one and her husband. *

On 12/12/2016 Diane said...

Just read some very interesting articles about L-Serine preventing or even treating ALS, Parkinsons and Alzheimers. Was glad to find l-SERINE AT BULK SUPPLEMENTS AT A GREAT PRICE. tHE PRODUCT IS VERY PURE AND PERFECTLY PACKAGED. wILL ORDER MANY OTHER SUPPLEMENTS FROM YOU IN THE FUTURE.*

On 11/29/2016 Robert said...

First Time Physician Purchase
I have been aware of safety studies on L-serine by investigators at for a while. Seems 10 grams daily best taken with carbohydrate or glucose for best absorption may help the brain repair twisted protein diseases ALS, Parkinson's and Alzheimer's. I have started my Mother and her husband on this product. Dosing seems easy. Product arrived quickly. *

On 11/13/2016 Richard said...

L-Serine Powder
I was looking for an l-serine supplement and found that Bulksupplements had the best price around. The powder is easy to mix with juice and I was a able to find a 40oz vacuum jar that fit the 2.2 lb bag perfectly. This is an incredible investment if the clinical research supports the claims of protecting against ALS, Alzheimer's and Parkinson's disease. I use 3/4 tsp=2grams per serving.*

On 10/26/2016 John said...

L-Serine - 500g Pure Powder
Hoping to improve brain health*

On 10/4/2016 VJ said...

Just bought this after the recommendation of a friend, who says it helps with memory. It arrived on time, good packaging, plenty of time before the expiration date. Mixed it in with my cereal in the morning. So far, so good.*

On 9/11/2016 Rynta said...

First time user
good pricing
high quality product
fast shipping
easy to use website
accurate description of product

once I opened the product, the packaging would not re-close properly and seal. seems to be a poor quality zip-lock *

On 9/9/2016 Karl said...

Hoping to improve brain health and sprint performance by taking l-serine in addition to phosphatidylserine
The following is a list of clinical trials, most double-blinded and placebo-controlled, found through a PUBMED search for "l-serine supplementation":

1. L-serine supplementation attenuates alcoholic fatty liver by enhancing homocysteine metabolism in mice and rats.
2. Lowering plasma 1-deoxy sphingolipids improves neuropathy in diabetic rats.
3. Oral L-serine supplementation reduces production of neurotoxic deoxy sphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1.
4. Oral administration of L-serine reduces the locomotor activity of socially isolated rats.
5. An essential role for de novo biosynthesis of L-serine in CNS development.

Stacks Updated 9/2/16:

The morning pre-workout stack (all BulkSupplements products at a daily cost of $1.04) that I drink thirty minutes before running three 50-second sprints is as follows:

1. Magnesium Citrate, 1.9 gram (0.285 gram elemental magnesium)
2. Potassium Citrate, 1 gram (0.36 gram elemental potassium)
3. Zinc Gluconate, 0.3462 gram (0.045 gram elemental zinc)
4. Ascorbic Acid USP, 8 grams
5. L-Lysine HCL, 1.25 gram
6. L-Proline, 0.4 gram
7. L-Serine, 0.5 gram
8. L-Ornithine HCL, 0.8 gram
9. N-Acetyl L-Cysteine USP (NAC), 0.9 gram
10. N-N-Dimethylglycine HCL (DMG), Vitamin B15, 0.5 gram
11. Methyl-Sulfonyl-Methane USP (MSM), 3 grams
12. Milk Thistle 80% Silymarin, 0.25 gram
13. Thiamine HCL, 0.1372 gram
14. Riboflavin, Vitamin B2 USP, 0.05 gram
15. Niacin, Vitamin B3 USP, 0.925 gram
16. Calcium Pantothenate, Vitamin B5, 92% Pantothenate, 8% calcium, 0.4326 gram
17. Pyridoxine HCL, 82% Vitamin B6, 0.2784 gram
18. Biotin 1%, Vitamin B7 in 99% DiCalcium Phosphate, 0.5 gram (5000 mcg biotin)
19. PABA, Para Aminobenzoic Acid Vitamin B10, 0.5 gram
20. L-Carnitine, Vitamin B20, 0.6 gram
21. Acetyl-L-Carnitine (ALCAR), Vitamin B20 (acetylated), 0.6 gram
22. Alpha Lipoic Acid USP, 0.5875 gram
23. L-Theanine USP, 0.6 gram
24. Vitamin A Palmitate (Retinyl Palmitate) (25000 IU), 0.1 gram
25. L-Citrulline DL-Malate (2:1), 0.5 gram
26. L-Arginine, 1.125 gram
27. Beetroot Extract, 1.75 gram
28. L-Taurine, 2 grams
29. N-Acetyl L-Tyrosine USP (NALT), 0.8 gram
30. L-Glutamine USP after exercise only, 2 grams
31. Green Coffee Bean, 95% caffeine, 0.3 gram
32. Creatine Monohydrate, 3 grams
33. Fenugreek Powder, 2 grams
34. Green Tea Extract, 50% EGCG, 0.25 gram
35. Rhodiola Rosea 3% Salidrosides, 1% Rosavins, 0.2 gram
36. Rutin USP, 0.1666 gram
37. DHEA (Dehydroepiandrosterone) Powder, 0.025 gram
38. Betaine HCL, 0.8 gram*

On 9/2/2016 Stephen said...

l-Serine and Alcohol Cravings
I want to share the personal experience I’ve had with L-Serine as there doesn’t seem to be any research on this amino acid related to alcohol cravings. I’ve undertaken the practice of not consuming alcohol for the past ten years. I fall off the wagon two to six times a year - so far. That is why I call it a practice. Thank god my addiction isn’t as bad as other people I have known (some who are no longer among the living.) Every time I fall off it’s like stopping all over again. I will have cravings at those magical hours, at seemingly consistent periods (7, 14 days.) So far, whether my slip continues for a couple weeks or is contained to a day or two, I have found the peace and serenity of abstinence again. Once on the wagon it’s like riding a bike. Just turning 60 I found my cognitive faculties degrading. I decided not to go willingly into the dark night so I researched supplements that might help. One was L-Serine. I bought it in bulk and started taking 5 - 8 grams in the morning. I won’t go into the other benefits, such as more energy, but what I came to realize after a pre-designated drinking ritual, my usual cravings were practically non-existent afterward. It might have been something else I started taking, but I’m pretty sure it was the L-Serine. Actually, when I lighten up on the dose, I have a greater sense of the danger. Maybe this could help someone else.*

On 7/25/2016 Ed said...

I got a micro nutrient blood test and the only thing I was deficient of was L Serene, which is included in Braggs Liquid Aminos but impossible to find anywhere but here. I was very significantly lacking in this non essential amino so don't have a story to tell yet as I have only been taking it a week or so, but the fact that this company has it... well that's pretty special right there. *

On 5/17/2016 Connie said...

Too early to tell!
My wife been diagnosed with ALS and she started taking L-serine and there hasn't been any changes yet to her condition, but we are willing to try anything. The powder mix dissolves fast.*

On 5/9/2016 Steven said...

L-Serine powder
Glad to have found Bulksupplements. The L-serine powder was packaged nice and neat with out all the fluff. The powder allows me to measure the dosage I need. The order arrived within 4 days. I will order again. Have already spread the word. thnx.*

On 4/25/2016 Denise said...

L-Serene Powder
I am taking this L-Serene Powder for an L-Serene deficiency as diagnosed by a cellular test. I have been taking L-Serene by capsule for about two years and wanted to use the powder due to its better cost. The product does dissolve nicely in water and barely has a taste. The powder enables me to advance from 1000 a day to 2000 a day in small steps. Also I have been very pleased with the service with Bulk Supplements.*

On 4/22/2016 Donna said...

Taking L-serene and feel steady gradual positive results in alzsheimers prevention*

On 4/13/2016 richard said...

This product lives up to its reputation. One reminder, though. Do not mix with cold water as it might not dissolve easily so if you wish to have a cold drink with it, dissolve the powder with a little bit of warm, preferably hot water first before adding the cold.*

On 4/11/2016 Graham said...

Like others, I heard about the trial of L-serine. I am hoping to find a benefit of this supplement to slow the progression of Progressive Supranuclear Palsy. The product is easy to use, product delivery was fast. The only question that remains is how much to use for positive results.*

On 3/5/2016 Christine said...

L-Serine powder
My wife has ALS and we read other reviews stating that this product may help her feel better. So far it seems to help her feel good. It dissolves fast and it ship to us quickly. Thanks!*

On 1/23/2016 Steven said...

After hearing about a medical trial using L-serene to help effects of ALS, Parkinson's and Altheizhmers I decided to try the amino acid for cognitive enhancement. I do believe it improves my attention span and keeps my memory sharper. *

On 12/13/2015 Gisele said...

L-serine powder
I started using this product for my husband when we found out he had ALS on Nov.16. I watched a video by Dr. Paul Cox about a study done using this product to help the twitching muscles, I called his research lab to find out the best L-Serine to purchase and it was the one from your company because it was pure and he said everyone in his lab used this product everyday. So for not I have very hight hopes it will help my husband. *

On 12/6/2015 Faye said...

L-serine powder
we have only been using it for 3 days, and are hoping it will help my husband, we just found out he has ALS and Dr. Paul Cox says that L-Serine has been shown to help them.*

On 11/19/2015 Faye said...

This product was recommend to us by our Doctor. Hopefully this product will help people suffering from a Motor Neuron illness. Ordering from this web site has been easy and the product arrives quickly. It dissolves well and from what hear it is taste less. I am thankful we found this company.*

On 10/23/2015 Pamela said...

as promised
Great product, dissolves easily, nifty package.Shipping was quick.*

On 10/21/2015 Kevin said...

L Serine
order received promptly and correctly. L serine wonderful product !*

On 9/20/2015 richard said...

Great product and fast shipping*

On 7/19/2015 Marcelle said...

use before bed helps me sleep. good for the brain as well*

On 7/18/2015 LAURA said...

L serine
My husband has been diagnosed with ALS. I've been researching the last 2-1/2 years and found bulk L serine at Bulk Supplements and truly believe it is helping. 30 grams a day is recommended and he notices a difference with increased fatigue and fasciculations if he misses more than a couple days. The product reaches us within a few days of placing an order which keeps me coming back. We thank you.*

On 6/16/2015 Kelly said...

Dear Friends and Readers,
I am 60 years old this year and confess to a rather unhealthy lifestyle for the better half of my life. I'm also educated and of course keen to study to avoid fads and snake oil. After my research I went on an informed nutritional voyage looking into supplements and foods that would fit my new lifestyle and pocketbook. Reading the recommended doses and buying the variety of products and taking one poll at ta time ended up with me swallowing handfuls capsules and pills opening jar after jar and filling my morning with the opening of bottle after bottle just to get my dose.
I discovered this website quite by accident and wow what a difference. I mix the products I use with my morning shake and can control my dosage. They combine and mix well with my other juices and this is seriously the most cost effective way to get on the program I'm on now.
L-Serine has elevated my mood and improved my memory at a level that I know there was a change in my health. Please do your homework before you do anything to change your health but also try this product. It's amazing and cost effective. *

On 6/14/2015 Tim said...

Super L-Serine
I would like to say thank you for the speedy delivery.... it was in my house in no time! I tried it and it relaxed me and made me feel refreshed and renewed and restored. I can't wait to try other wonderful supps from, as they will be my main supplier of good and healthy supplements from now on. *

On 6/11/2015 Juan said...

L-Serine for ALS
I started L-Serine last week for ALS. I am in a wheelchair, paralyzed from the waist down. I live near many bodies of water and grew up swimming in a lake, so it is very likely I ingested a LOT of cyanobacteria. I'm 45 and was diagnosed with ALS at age 43 and have been wheelchair-bound for almost three years. In the past week, my hands and arms, which I am losing, ached and my fingers were hard to bend about half an hour after I took my 4 tsp. in the morning and 4 tsp. at night. The ache went away after a few hours. This week, I am not getting the aches and pains and I feel GREAT. I am hoping this is doing what I think it is doing and it is not just a placebo affect. I will come back in the months that follow and report back on my progress. Google 'TedTalk The Secrets to Alzheimer's Dr. Paul Cox' if you want more information as to what I am talking about. *

On 5/4/2015 Rachel-Wisconsin said...

I thought I gave this 5 stars, but it looks like I only gave it 1...anyway the product mixes & tastes great. Hope it will stop ALAS progression.*

On 4/21/2015 carole said...

This is my first experience with L-Serine. Your bulk product mixes well and the taste is quite good. I was diagnosed with limb onset ALS two years ago and I, like Pete Peterson, hope L-Serine will slow or stop the progression of this terrible disease. Pete reviewed this product over 1 year ago. It would be great to know how this has worked for him. Also, the research team told me they have had better success with higher doses of L-Serine. They do not offer medical advice, however 30 grams per day was acceptable. I take 15 grams in the AM & 15 grams in the PM. Keep the faith PALS!*

On 4/20/2015 carole said...

Gentlemen, This is the second bulk order I have placed with your company. I love your product in the pure powder from, because when I mix it up with water, it goes completely clear. I have used the capsules before. This was before I found your website, and I took the capsules apart. The powder in the pill form mixed with water, when I stir it up, it was very cloudy, like impurities in the L.Serine. But your powder form is the best like I said it mixes up clean and the taste, it reminds me of a sugar taste.
I was recently diagnosed with upper Bulbar ALS. I read that the University of Phoenix is conducting a trial with L.Serine, so I called and they told me how to take it. I take 15 grams a day. 7.5 grams in the morning and 7.5 grams in the evening. This trial test is to see if L.Serine will slow down the progression of ALS or stop it completely. I have been on it for now 2 months and the test is for 6 months. So I will be ordering the bulk form as I have done in the last two orders from you. Thank you for getting this product to me. I hope this L.Serine will slow this death sentence disease for all the people who have it. Take care, I hope this review will be some value to you.
Pete Peterson *

On 2/12/2014 Pete Peterson said...

Only registered users can write reviews. Please, log in or register

Product Questions

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i want buy for my baby how much to feed one day for 6 month old baby (current weight: 18lb) could i know shelf-life period?! And after opening ,best before?! does it eat with powdered milk?!
Hi You recommend 2000 mg of the l-Serene powder but only sell it in grams. What size should i order?
does this product contain any d-serene