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Betaine Anhydrous Trimethylglycine (TMG) Powder

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Price From: FROM $10.96

Ships Monday, October 24 if ordered in the next 2 days, 19 hours and 20 minutes!

Betaine Anhydrous Trimethylglycine (TMG) Powder

Key Features

  • 100% TMG powder
  • May aid in Carnitine production
  • Supports overall health
  • Taste

  • Mixability

Betaine Anhydrous is a derivative of Choline and is an important nutrient. It is also known as Trimethylglycine (TMG).


Serving Size & Timing

The serving size for Betaine Anhydrous sits at anywhere from 750mg (1/4 tsp) to 1500mg (1/2 tsp) to be taken once daily, depending on intended effect.

Nutritional Information

Supplement Facts

Serving size: 1500 milligrams
Serving per container: *
Amount Per Serving % Daily Value**
Trimethylglycine (TMG aka Betaine Anydrous) 1500mg *
* Daily Value not established.
** Based on 2,000 calorie diet


Sugar, soy, dairy, yeast, gluten, corn and additives..

As a dietary supplement, take 750mg (rounded 1/4 tsp) to 1500 mg (rounded 1/2 tsp) daily, or as directed by physician. Suggested amounts vary with age and fitness.

US Standard Measuring Spoons
Spoon Size(level) milligrams
1/4 teaspoon 606
1/2 teaspoon 1212
1 teaspoon 2425



There are no anti-caking agents or any other kinds of fillers present in this supplement, as it is entirely food grade.


Other than the usual side effects that might be suffered by anyone that takes too much of any supplement (nausea, upset stomach, diarrhea, etc.), there are no other reported side effects. As with most other supplements, a doctor should be consulted before taking it, and women who are lactating or pregnant should avoid it until adequate consultation has been received.


Betaine was first identified in sugar beets in the 19th century. It can also be found in many different dietary sources including beans and legumes, grain cereals, wine, seafood and leafy green vegetables.

This supplement can be taken in conjunction with Creatine Ethyl Ester Malate, Creatine Monohydrate or Creatine Ethyl Ester for muscle mass gain. The taste of Betaine Anhydrous could well be described as sour or tart. It can be mixed easily in a variety of solutions as long as they are heated beforehand. This includes plain water. There is also a taste difference between the more mild form of Betaine and the potent HCL Betaine.

Customer Reviews

This is a great energy stack for hubs and I when we work out. We take ribose, glutamine, and TMG together. It increases energy levels before workouts and alleviates muscle soreness after. *

On 6/21/2016 Mike and Kim said...

great pre work out additive
I mix this product with my workout and it has given me a great pump, makes my muscles feel full when working out. Would recommend to use pre and post workout.*

On 6/18/2016 christopher said...

Good for workouts
We use this with ribose (also bought from Bulk Supplements) and glutamine for workouts: Ribose and TMG before, glutamine after. All work great and we will be reordering TMG to retinue this great combo.*

On 6/13/2016 Mike and Kim said...

Thank you again, bulk supplements. ordered betaine for a sample and
put it in my preworkout powder. I make my own with the ingredients I
know work. this is a great addition, my strength and size have grown
greatly since bicep surgery. great powder. pure and again thank you
bulk supplements.*

On 6/6/2016 michael said...

Great product
There are a handful of supplements that have real studies to back them up and this is one of them.

I like to make my own preworkout so I know what I am getting, no "proprietary blends." I buy everything from BulkSupplements--great products and fast shipping.*

On 5/11/2016 Jennifer said...

-TMG -
I got my hands on some of this TMG, because I thought that it might be something like the amino acid Glycine. Glycine is one of the supplements I use the most for its powerful neurological benefits.

This did not turn out to have the same properties that Glycine does, but it's nice to have around. I gives you a tingly pleasant feeling, and kind of a rush after you take it. It has a sweet taste, and that vague rotten fish smell that some of the powders have.

If you are working out, and you make stacks for yourself or others, this powder really is something to have in there with the other stuff. It's great to work out hard and drink a protein shake and feel it working. With a little bit of this in there, you'll need to sit down for a while to let the buzz wear off. Nice.*

On 4/24/2016 H. said...

great product
It mixes well and I love it for my PWO stack. It has improved my workouts since I tried it.*

On 3/21/2016 Andrew said...

great product
It mixes well and I love it for my PWO stack. It has improved my workouts since I tried it.*

On 3/21/2016 Andrew said...

When I take creatine and TMG together I get a great pump, great product*

On 2/9/2016 CHAD said...

I have researched this product and found very good critiques on line. I ordered some last week and added it to my pre and post-workout stack. I can already tell a difference in my lifts in this short amount of time. I order all of my supplements from bulk supps... I recommend a 2-2.5 gram dose before and after your workouts.*

On 2/1/2016 Austin said...

This is yet another great product from, It is very pure and a great addition to your stack. I make my own pre and post work out drinks from supplements I buy from bulksupplements, this is my newest addition and well worth the money. Try it!*

On 1/11/2016 John said...

Great for the endurance runner
I use this in my homemade pre-workout mix. It is much cheaper buying each ingredient from compared to buying some other company's pre-workout mix. This makes a real difference in my workouts and races, and I would highly recommend to any serious endurance athlete. I will be buying again!*

On 1/8/2016 Emily said...

Best TMG
I have MTHFR. TMG is great for me. Bulk supplements has the best products.*

On 12/16/2015 Susan said...

Make Your Own Blend
To avoid harmful additives, I suggest you research your specific needs and blend the pure supplements yourself. I trust 'Bulk Supplements' to provide the highest quality ingredients for my own needs.*

On 12/14/2015 Gabe said...

Great mixability
Mixes great. Good for PWO.*

On 12/7/2015 Peter said...

Excellent supplement in PWO Stack
Read about this product and im so glad i added it to my PWO Stack, great stuff. Got here in only 3 days! Free shipping, works great inside the gym. Makes me feel great, and its amazing for your liver. Will be ordering again.*

On 11/22/2015 Michael said...

Great value.
Best price on Betaine that I have found. Excellent quality and Bulksupplements shipping was extremely fast. Love their stuff. *

On 11/4/2015 jeremy said...

Very good product
My strength and stamina are always consistently rising when I use this product. Very easy to consume with my preworkout drink . Great price in my opinion as it truly does give me that edge my body needs. I'm thankful to Bulk Supplements for supplying this product. *

On 10/21/2015 Tim said...

The Come Back!
Betaine is extremely underrated and underused amino-acid,that's about to make a huge comeback in bodybuilding world,love this product, helps build muscle by increasing protein synthesis and boost performance at the gym. YOU NEED THIS IN YOUR STACK A S A P !*

On 10/3/2015 Richard said...

Excellent product
1.5 grams pre and post workout help with strength gains. Product is clean. Has a slightly fishy odor but you cannot taste this when mixed. Overall very satisfied!*

On 9/29/2015 Zach said...

Betaine the good stuff!
It has been less then 1 week, and this product is simply amazing! The performance you get from this stuff is awesome! Perfect for the athlete who is on a mission to reaching their real goals. Gains, reps, & the high performance that is reachedone is soo great! & not only that, delivered my product in just 3days!!! I will definitely be ordering my products from here again!*

On 8/10/2015 Erick said...

Great pumps, great customer service
I've only used this for three days but can already say that I get insane pumps and my muscles feel very full. As for bulk supplements, I received my order within 3 days. I will order from them again.*

On 7/25/2015 Chris said...

Betaine!! Beast
This stuff is the best way to make gains in mass, reps, or overall performance. For a boost mix it with beta-alanine and creatine or even Alcar. This product doesn't get the respect it deserves just yet but its getting some hype. So get ahead of the curve!!*

On 7/25/2015 Eric said...

Impressively quick shipping. Bulk Supplements sets the standard for excellence
TMG is a vitamin-like substance. It functions as an energy booster, methyl donor and more. TMG is also called betaine because it was first isolated from sugar beets. TMG is not the same thing as betaine hydrochloride. It is typically consumed in doses of 1000-3000 mg daily.

TMG is used for:

1. Lowering homocysteine. Homocysteine is an amino acid that, in excess, is irritating to the arteries and is strongly associated with inflammation and hardening of the arteries. In fact, the level of homocysteine correlates much better with heart disease than high cholesterol.

Homocysteine is becoming better known these days but why has it taken so long? Even where it is mentioned as a major marker for heart problems, the advice is to take
- B6, best as pyridoxal-5-phosphate, the form it takes in the body
- B9, best as methyl-Folate - not folic acid, which is synthetic and can cause cancer
- B12, best as methyl-cobalamin, not cyanocobalamin (lacks methyl groups)

These B vitamins are important and deficiencies of B9 and/or B12 can cause anemia well as other major health problems (and they should always be taken together). However, TMG is more effective than any of these for lowering blood homocysteine levels.

TMG is a methyl-group donor, which degrades to DMG when it has donated one methyl group to homocysteine to render it harmless. It acts in DAYS to bring down the blood homocysteine level.

High homocysteine occurs when there is not enough TMG or B9/B12 to donate enough methyl groups. There can be other causes, but this is the major cause. A deeper cause for this is the presence of mercury and copper toxicity, which are almost universal. However, the problem can be solved with a diet high in TMG and folate/B9 (must always be taken with B12, as they are partners in many body processes).

High homocysteine accumulates in the blood and is toxic to blood vessels, causing plaque formation which leads to occlusive vascular disorders such as coronary artery disease, heart attack, stroke, mini-stroke, deep vein thrombosis, and narrowing of arteries. High homocysteine, however, causes many other problems. It causes a deficiency of methionine, and this, in turn, can cause a deficiency of SAMe, causing depression in some people. Methionine is also needed for other biochemical reactions involving protein synthesis, another critical body function. In fact, reducing excessive homocysteine helps with conditions ranging from osteoporosis and birth defects to cancer and aging. It also helps with antioxidant protection, as well.

#2. Helping with liver detoxification. Methyl groups are absolutely essential for the Phase 2, P450 liver detoxification pathway. Within this critical biochemical sequence of events, fat-soluble or otherwise poorly soluble toxins that are difficult for the liver to remove are joined to a methyl group, and this helps prepare them for removal from the body. This is an amazing and vital chemical detoxification ability. In MOST people, it does not work well due living in a very toxic world.

Specifically, the methylation reactions enables toxins to become much more soluble in water. This allows the body to remove the toxins much better, and it often neutralizes some of their toxic properties, as well. These toxins include all of the toxic metals in many forms and compounds, as well as hundreds of toxic chemicals. Much more could be written about this amazing system and how critical it is today for our health. This is one of the main benefits of TMG supplementation, I believe.

#3. Alleviating depression. TMG increases the body's natural production of SAMe or S-adenosyl methionine. This chemical can help reduce depression, in some cases. SAMe is an expensive supplement and does not seem to be as effective as TMG.

#4. Reducing the chances of diabetes. Methyl groups are involved in insulin release and insulin activity. When the body does not have enough active methyl groups, diabetes is much more likely to arise.

#5. Avoiding genetic problems. Methyl groups are needed for protein synthesis, also called biosynthesis. This is the copying of our genetic code from the DNA to RNA, and then from there the synthesis or formation of every chemical in our bodies. The copying of the DNA is also called genetic transcription.

Without enough TMG, biosynthesis can slow down, telomeres can shorten, and genetic errors, also called transcription errors, multiply, and health is definitely worse.

#6. TMG is good for those with an MTHFR defect. Over 50% of the world's population today has a mild to severe copying error in their cells that reduces the biosynthesis of folate in their bodies. This is mistakenly called a "genetic defect", when it is no such thing. It is a transcription error or polymorphism or abnormal gene expression. This is an error in copying the DNA code, and not a problem with the DNA code itself.

#7. Profound effects on the brain, digestion and other body systems. TMG seems to affect many body systems, probably because methylation reactions are vital throughout the body.

Antioxidant and anti-inflammatory effects are claimed and appear to be true, although there does not seem to be much medical literature about them.

Side effects. A few people do not tolerate TMG well. They may just not need very much of it. However, research indicates that, in some cases, the problem is that it brings up psychological issues or it detoxifies them too quickly.

In particular, men or women who have deep-seated resentments and perhaps some ambivalence about men seem to have more trouble taking TMG. It appears that TMG activates an enzyme system that is dormant or less active in those with male resentment issues. Taking TMG, for these people, can cause rather severe symptoms or anger, fear, depression or anxiety.

If this occurs, just reduce the dosage to a comfortable dose. The symptoms promptly go away when one reduces or stops the TMG. However, if one can tolerate the symptoms, one may move through the retracing of relationship issues much faster, so take what you can.*

On 6/23/2015 JSB said...

TMG Review
My order for TMG was delivered in a timely fashion well ahead of five other supplements ordered on the same day.. Bulk shipments understands the importance of prompt service to customers who might depend on the ordered product for good health*

On 6/9/2015 Charles Robertson said...

Betaine Anhydrous Trimethylglycine (TMG) - 1kg Pure Powder
This is my second purchase for this product. I do not use or buy premixed supplements anymore. I buy in bulk and make my own pre work out and post workout mixture. Betaine Anhydrous Trimethylglycine (TMG) Pure Powder is an excellent product and through search and study I found this to be the best deal on the internet. delivery is fast and on time and with free shipping over 49$ or more, you just cannot beat it.*

On 6/8/2015 GEORGE said...

Pre Workout Stack
Adding into my pre-workout stack. I take BCAAs, L-Citrulline, Glutamine, AAKG, and now this TMG (betaine) and will be adding in DAA. Needed TMG to add in DAA to offset any side effects from DAA. This stuff gives you added energy can tell right away. Best price online for almost all products on the site.

Beware of smell it's fishy but that's normal for betaine. I did notice my breath smell a little fishy, even after brushing my teeth, but I need to supplement with more vitamin B2 (riboflavin) to decrease this. Supposedly 200mg of B2 will help with this odor. Based on studies 1.2 grams of betaine taken 2 times a day is the correct amount to see added workout improvements. Will try this and see if I notice a big increase.


On 5/31/2015 Robert said...

Good Product
Shipped quickly, got exactly what I wanted. It came in a resealable bag which is nice. Will be buying from here again.*

On 5/17/2015 Connor said...

Great product
Great product. Packaged well and exactly what is expected, pure TMG. Tastes and smells good. Fast delivery. Very satisfied.*

On 5/12/2015 Alexander said...

Adrenaline rush
Great stuff gives me lots of energy in the gym. It works even better with the L-Lysine HCL and L-Arginine HCL that Bulk Supplements carry . Best products and price out there!*

On 5/2/2015 eric said...

TMG - As pure as it gets.
I have recently become interested in this product. Trimethylglycine functions as an anti-oxidant, anti-inflammatory; it boosts energy and it is a methyl donor. It protects the liver and lowers homocysteine.

I want to get away from regular vitamins with their fillers and additives and the bulk products at BulkSupplements arae excellent.

An excellent product, very clean, nicely packed and shipped promptly. I would very much recommend this.*

On 5/1/2015 Anne said...

Great for Methylation Support!
Love this bulk version of TMG, as I not only use it for myself, but also for my two horses and my little dog! Many (but not all) of us can be helped by more "methyl donors" and I have found this nice, clean, free of junky additives product to be a great addition to my supplements. At this great price, it makes using it for my larger "family members" very reasonable. Homocysteine level is now at 6! Right where it belongs! Great products.... (I use several other things too) Fast Shipping.... What more can you ask for?? Thank you Bulk Supplements!*

On 4/14/2015 Kim said...

Excellent supplement. Using in a pre- and post-workout drink mix along with Creatine Monohydrate, Beta Alanine, L-Citrulline DL-Malate, and BCAAs (2:1:1). Highly recommended. *

On 3/10/2015 Blake said...

Keeps me going
I had heard that the Auburn football team uses beet juice to help keep them going during football games so when I read that TMG is derived from sugar beets I tried it out. I must say, especially when doing HIIT, I can tell I have more endurance and don't tire so quickly.
This is now part of my daily pre-workout drink and BulkSupplements is my sole source supplier!*

On 3/9/2015 Tom said...

What can I say? Got it fast, got a very reasonable price, does exactly what I wanted it to. Bulk Supp is the best.*

On 3/3/2015 Brian said...

TMG powder
I'm taking this product to reduce my homocysteine levels. I thought I could mix it with water, but I find the odor is too strong, so I'm making capsules out of the powder. Note that since there are no anti-caking agents the powder does clump up a bit, even for capsules, but overall I'm very satisfied. Perhaps Bulk Supplements could make this available in crystal form??*

On 12/9/2014 Sam said...

Good Stuff
This was my first time purchasing Betaine TMG from Bulk Supps, but I've purchased TMG elsewhere before. I can say without a doubt this is good TMG - tastes, smells, and looks exactly like it should so I know it's legit!

Betaine TMG has a wide variety of health benefits and can even help increase power output in the gym. I can personally attest to the power output benefits as someone who has been lifting 5 days a week for the past two years - the effect is quite subtle but noticeable. Betaine TMG also helps with the uptake of creatine which is another great benefit to lifters.*

On 12/4/2014 Matt said...

Trying it out....
I take quite a few supplements for health and training. I used one of my free samples to try this out. I'm very impressed by the customer service of Bulk Supplements and look forward to seeing if I'll add this to my regime. *

On 10/18/2014 Paul said...

A plus for my hair care lint
I bought this to add to my honey line of hair care products. I like it because of its anti inflamitory and anti bacterial properties. It is also nstural which makes it a good selling point. • Improved hair strength.
• Retention of its initial resistance to yield for a longer period.
• Less prone to fracture.

On 8/17/2014 abigail said...

Tmg powder
This is the first time trying out this supplement.
It has many benefits but foremost it helps to detox heavy metals!
I am super stoked and look forward to more wonderful products like this one.!!!! Great price!*

On 6/17/2014 angelina said...

Increases Power Output
A study where subjects took 1.25g of TMG twice daily, noticed an increase in power output. There were also slight increases in volume and endurance. While this was only one study, the anecdotal support for this supplement is strong.

I have been adding in 1.5g to my pre and post workout shake for the past month and have been setting new PRs since then. This supplement was the only addition during this time with my calories kept constant.*

On 6/9/2014 Matt said...

Betaine is Off the Charts
For some of you that don't know, betaine has been shown to increase athletic performance and the uptake of creatine and amino acids. Not only that, it is an effective lipotropic agent. It mixes quite well, and has been working just fine. I feel good in the gym while supplementing this into my morning amino drink. Solid product and part of my every day routine.*

On 4/19/2014 zac said...

Good Product & Company
I decided to try Betaine Anhydrous after reading a lot about it recently as it seems to be gaining in popularity and has some scientific backing. It is more popularly none as TMG and in most places i looked was sold in capsules.

I chose this product from bulk supplements since it is sold in bulk powder form--it is much cheaper than the capsules and I can measure out the amount I want and easily mix as desired. I usually take it with creatine as it is supposed to help with creatine uptake.

This was my first order from this company and they shipping was quick (same day in this case) and product was well packaged and everything was professional. As with most supplements, the effectiveness of the supplement is up for interpretation, but I'm sufficiently satisfied after a few weeks of use to continue evaluating. If your looking to try it or already use it, i would recommend this as quality source.*

On 1/10/2014 RH said...

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